I'd like to do a stream - just my brother and I BSing about random shit. Anime and manga we've discovered, webcomics, movies, games, original fiction, versus debates, hardware, software, rare and unusual cars, the way of the bachelor's kitchen, and even guest speakers (probably more often than not our other brothers at first).
I have it on good authority that people find the stuff we wind up talking about to be Interesting and/or Amusing.
(Best part? "Hi! I'm Ben." "And this is Sam." "And together..." "...WE'RE BS!")